Based on function:
* Whisper: This implies a quiet and private way of speaking, the opposite of a megaphone's loud and public amplification.
* Microphone: This focuses on capturing sound rather than amplifying it.
* Muffler: This reduces sound, the opposite of a megaphone's amplification.
Based on size:
* Earphone: This is a small device used for listening, the opposite of a megaphone's size and purpose.
Based on purpose:
* Silencer: This is used to reduce noise, the opposite of a megaphone's purpose of amplifying sound.
Ultimately, the best antonym depends on the specific situation you're describing.