Spanish:
* re-YENO (emphasis on the second syllable)
English:
* re-LEN-oh (emphasis on the second syllable, with the "o" sound like the "o" in "go")
Context:
* In Spanish: "relleno" is a common word meaning "filling" or "stuffing".
* In English: "relleno" is often used to refer to a dish, usually a stuffed pepper, in Mexican cuisine.
Therefore, the pronunciation will vary depending on the context.