1. Paper: A quire is a bundle of paper consisting of 24 sheets. This is the most common meaning of the word, especially in printing and bookbinding.
2. Choir: In the context of music, "quire" can be an older, less common word for choir. It is sometimes still used in the names of some choirs, such as "The King's Chapel Choir".
3. Church: In the context of architecture, "quire" can refer to the space in a church where the choir sits. This is sometimes also referred to as the chancel.
4. Book: In the context of bookbinding, "quire" can refer to a section of a book made up of multiple folded sheets. This is similar to the definition of quire as a bundle of paper, but specifically refers to how the paper is folded and used within a book.
The specific meaning of "quire" will usually be clear from the context in which it is used.