Here are some examples of words with the suffix "-cule":
* Animalcule: A tiny animal, especially one visible only under a microscope.
* Molecule: The smallest unit of a substance that has the chemical properties of that substance.
* Corpuscle: A small particle, especially a blood cell.
* Vesicle: A small sac or bladder containing fluid.
So, while "cule" by itself doesn't have a specific meaning, the suffix "-cule" is used to indicate something small or diminutive.