It can refer to:
* The state of being absent: "La ausencia de luz en la habitación era inquietante" (The absence of light in the room was unsettling).
* The act of being absent: "Su ausencia en la fiesta fue notable" (His absence from the party was noticeable).
* The feeling of missing someone or something: "Sentía una profunda ausencia en su corazón" (He felt a profound absence in his heart).
It's a word with a lot of emotional weight, often used to describe a feeling of loss or longing.