For literal darkness:
* Darkness: This is the most straightforward option.
* Gloom: Implies a heavy, oppressive darkness.
* Shade: Can refer to a lighter form of darkness, like the shadow of a tree.
* Obscurity: Refers to a state of being hidden or unknown.
* Night: Specifically refers to the period of darkness after sunset.
For figurative darkness:
* Mystery: Can refer to something unknown or hidden.
* Ignorance: Refers to a lack of knowledge or understanding.
* Despair: Can refer to a state of hopelessness or sadness.
* Evil: Can refer to something morally wrong or harmful.
The best choice will depend on the specific meaning you want to convey.