It can also be used for "godmother", but in that case, it's common to add "de batismo" (baptism) for clarity: padrinho de batismo (godfather) and madrinha de batismo (godmother).
It can also be used for "godmother", but in that case, it's common to add "de batismo" (baptism) for clarity: padrinho de batismo (godfather) and madrinha de batismo (godmother).