The word is essentially a made-up word from the movie "Mary Poppins," meant to be a nonsensical expression of something wonderful and amazing.
Here's why it's tricky to find an opposite:
* It's subjective: What one person finds "supercalifragilisticexpialidocious" another might not.
* It's not a specific thing: It's a feeling, a state of being.
If you're looking for something to express the opposite of "supercalifragilisticexpialidocious," you could use words or phrases like:
* Dreadful
* Abysmal
* Horrible
* Miserable
* A complete disaster
* A real downer
Ultimately, the best opposite would depend on the specific context you're using it in.