Formal and Respectful:
* Elder
* Senior citizen
* Veteran
* Mature individual
* Experienced person
* Wise person
Informal and Positive:
* Old timer (can be affectionate)
* Old hand (implies experience)
* Grandfather/Grandmother (if age is the focus)
* Wiseacre (can be playful)
The best antonym will depend on the specific situation and the intended tone.