As a noun:
* The heavy burden of responsibility weighed heavily on his shoulders.
* She carried the burden of her family's expectations.
* The financial burden of college tuition is significant for many families.
* He tried to relieve her of the emotional burden she was carrying.
As a verb:
* The company was burdened with debt.
* Don't burden yourself with unnecessary worries.
* The new regulations burdened small businesses with additional paperwork.
* I wouldn't burden you with my problems if I didn't need your help.
In a figurative sense:
* The news of her illness was a heavy burden on her family.
* The country was burdened by a history of war and violence.
* The new law burdened free speech with unnecessary restrictions.